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Jupiler Pro League 2025/26: Matchday 21 Betting Tips

It is nearly time for the first round of Jupiler Pro League fixtures in 2026.

The winter break may have come at the right time for a few teams, perhaps table-toppers Union Saint-Gilloise, who currently lead Club Brugge by just a single point after a tricky run of results.

Of course, the two Pro League leaders have a place in our latest round of betting tips, all of which feature the best odds for your weekend bets on football.

*All odds are subject to change

Club Brugge vs La Louviere: Result after 30 minutes – Club Brugge @ 2.26

After a shock 2-0 midweek loss at Charleroi in the Croky Cup quarter-finals, Club Brugge really need a fast start when La Louviere come to town. Ivan Leko’s side is packed full of talent, and with the gap to USG so small, they can surely make this a tough evening for La Louviere – who were beaten 2-1 by Royal Antwerp in the Croky Cup on Tuesday evening. Club Brugge are also out for revenge after suffering a 1-0 loss at La Louviere back in September, so we are backing the hosts to come out firing, grabbing a goal in the first half hour of play.

Zulte Waregem vs Genk: Draw @ 3.65

This is a battle between two sides really struggling for form in the Pro League. Genk are four matches without a win, while Zulte Waregem last claimed a top-flight victory back in October. But Zulte Waregem have at least drawn five of the last seven in the Pro League, and were last beaten on home soil in November (1-4 vs USG). Combine that with Genk’s poor away form – winless in three on the road – and the odds for a draw really leap off the page.

Union Saint-Gilloise vs Mechelen: Anytime goalscorer – Promise David @ 1.90

David is the joint-top scorer in the Pro League this season with eight goals in 18 appearances. The Canadian centre forward has netted twice in his last three top-flight appearances, and was also on target in USG’s 2-0 win over Dender in the Croky Cup quarter-finals. David Hubert needs his main man firing over the next few months for the team to stand a chance of retaining the Pro League crown, and the signs are looking very good indeed. Fifth-placed Mechelen have kept just one clean sheet in the last six across all competitions, so on home soil, David should be able to continue his positive form in the final third.

Royal Antwerp to beat Dender @ 2.45

After a run of five matches without defeat, including three Pro League victories, Dender are winless in four following the aforementioned loss to USG in the cup. Antwerp’s 2-1 victory over La Louviere should have put them in good stead for this trip, and revenge will be on the minds of the squad after losing 2-1 at home to Dender on November 23. And we are backing Antwerp to get the job done as they look to secure a place in the Championship Round, currently sitting seventh in the table, behind Standard Liege on goal difference only.

 

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